Return to Vascular Anomalies Center    Dept. of Otolaryngology    UAMS

Gal Shafirstein, Ph.D.
Director of Vascular Anomalies Research
Arkansas Children’s Hospital
Department of Otolaryngology
Jackson T. Stephens Spine Center
University of Arkansas for Medical Sciences
501 Jack Stephens Drive
Little Rock, Arkansas 72205

Tel. 501 526 4917

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Specialties: Laser-tissue interaction, image analysis, mathematical modeling and medical device development.
Team Role: Translational research, mathematical modeling of laser-tissue interactions in port-wine stain, and new imaging modalities for diagnosis of vascular lesions.

[ Other team members ]

Gal Shafirstein, Ph.D.


Dr. Gal Shafirstein was born and raised in Israel. In 1992 Dr. received his Ph.D. from the materials department at the Technion Israel Institute of Technology in Haifa, Israel. During his studies Dr. Shafirstein was recognized with four awards for distinction in research and studies.

Dr. Shafirstein joined Arkansas Children’s Hospital Research Institute in 2001. In 2002, he was the recipient of the New Scientist Development Marion B. Lyon Award for the Mathematical and Pathological Analyses of the Response of Port Wine Stains to Pulsed Laser Treatment. Working closely with the physicians of the vascular anomalies team, he developed a new mathematical approach to predict clinical outcomes of laser treatments of vascular malformations. He also developed a thermal ablation technology to reduce local recurrences of cancer following the initial surgery. His research work has been supported by the U.S. Army medical research and Material command and the National Cancer Institute at the National Institute of Health.

Dr. Shafirstein is co-inventor of four novel technologies in Bioengineering and a founder and manager of two UAMS BioVenture companies. He serves on the review board for the U.S. Army medical research and Material command breast cancer program, and regularly reviewing papers for leading journals in his field of expertise.

Selected papers:

G. Shafirstein, W. Bäumler, M. Lapidoth, S. Ferguson, P. E. North and M.Waner. A New Mathematical Approach to the Diffusion Approximation Theory For Selective Photothermolysis Modeling And Its Implication In Laser Treatment of Port-Wine Stains. Lasers in Surgery and Medicine 34:335–347 (2004).
Lapidoth M, Shafirstein G, Ben Amitai D, Hodak E, Waner M, David M. Reticulate erythema following diode laser-assisted hair removal: a new side effect of a common procedure. J Am Acad Dermatol 2004;51(5):774-7.
Babilas P, Shafirstein G, Bäumler W, Baier J, Landthaler M, Szeimies R and Abels C. Selective Photothermolysis of Blood Vessels following FPDL-Irradiation: in vivo Results and Mathematical Modelling are in Agreement. J Invest Dermatol 125:343 –352, 2005.
Wolfgang Baumler, Annegret Vogl, Michael Landthaler, Milton Waner and Gal Shafirstein. Port wine stain laser therapy and the computer-assisted modeling of vessel coagulation using the finite elements method. Medical Laser Application 20 (2005) 247–254
Bäumler W, Ulrich H, Hartl A, Landthaler M and Shafirstein G. Optimal parameters for the treatment of leg veins using Nd:YAG lasers at 1064 nm. Br J Dermatol 2006; 155(2):364-371
Mutlu Mete, Xiaowei Xu, Chun-Yang Fan and Gal Shafirstein, "Head and Neck Cancer Detection in Histopathological Slides," Sixth IEEE International Conference on Data Mining - Workshops (ICDMW'06), icdmw, pp. 223-230,2006.
Baumler W, Vural E, Landthaler M, Muzzi F and Shafirstein G. The effects of intense pulsed light (IPL) on blood vessels investigated by mathematical modeling. Lasers Surg Med 2007;39(2):132-9.
Shafirstein, G., Buckmiller, L. M., Waner, M., and Baumler, W. Mathematical modeling of selective photothermolysis to aid the treatment of vascular malformations and hemangioma with pulsed dye laser. Lasers Med Sci, [publish online ahead of print] Feb 7, 2007.
Babilas, P., G. Shafirstein, J. Baier, V. Schacht, R.M. Szeimies, M. Landthaler, W. Baumler, and C. Abels. 2007. Photothermolysis of blood vessels using indocyanine green and pulsed diode laser irradiation in the dorsal skinfold chamber model. Lasers Surg Med. 39:341-352.
G. Shafirstein, L. Hennings, Y. Kaufmann, P. Novak, E. G. Moros, S. Ferguson, E. Siegel, S.V. Klimberg, MD, M. Waner and P. Spring. “Conductive Interstitial Thermal Therapy (CITT) Device Evaluation in VX2 Rabbit Model “, Technology in Cancer Research and Treatment, [publish online ahead of print], June, 2007.